Polymorphisms in PLAT (e.g., tPA‐7351C/T, tPA‐Alu insertion/deletion [I/D], tPA‐25 I/D) have been reported to be associated with clinical disorders such as stroke,11, 12, 13 myocardial infarction,14, 15 temporal lobe epilepsy (TLE),16 and increased susceptibility to some bacterial infections.17, 18. This evidence concerns the gene PLAT and bacterial infectious disease.