AZD7762, a CHK1/CHK2 inhibitor,250 honokiol or tunicamycin are less cytotoxic to NSCLC cells, but can cause accumulation of DSB damage, arrest cells in G2/M phase and induce apoptosis, which may enhance radiosensitization of NSCLC cells exposed to carbon ions rather than X‐rays.248. The gene discussed is CHEK2; the disease is non-small cell lung carcinoma.