CETP and glycogen storage disease VI: This protein regulates the concentration andparticle size of HDL-C in the blood and plays an importantrole in reverse cholesterol transport (Barter, Kastelein, 2006).It has been shown that elevated activity of CETP reducesHDL-C concentration and correlates with a higher risk ofcardiovascular disease (Barter, 2011; Iwanicka et al., 2018).Variants in the CETP gene can alter the blood lipid profile(Wuni et al., 2022).