LDLR and familial hyperaldosteronism: One substitutionis located in LDLR exon 3 (NM_000527.5:c.266G>C,NP_000518.1:p.Cys89Ser), in which at this position, rare likelypathogenic variant rs875989894 NM_000527.5:c.266G>A,NP_000518.1:p.Cys89Tyr has been previously describedin patients with FH (Day et al., 1997; Graham et al., 1999;Fouchier et al., 2005).