There was a significant decrease of WP (from 57% to 49%, p > 0.001), Pi10 (from 0.32 mm to 0.26 mm, p = 0.004), the WT G4-8 (from 1.60 mm to 1.37 mm, p = 0.004) and a significant increase of LA G4-8 (from 20 mm2 to 24 mm2 (p = 0.003), number of segmentable airways (from 122 to 204, p = 0.018) and bronchiectasis index (from 2.77 to 7.38, p = 0.012). The gene discussed is SERPINB10; the disease is bronchiectasis.