The stabilization of target genes responsible for encoding glycolytic enzymes and the pro-inflammatory cytokine IL-1β, which can impede tumor cell growth, enhance tumor survival, and intensify inflammation, is facilitated by this process (O'Neill and Pearce, 2016; Selak et al., 2005; Liu et al., 2016; Aspuria et al., 2014) (Figure 1). This evidence concerns the gene IL1B and neoplasm.