EPAS1 and chronic myelogenous leukemia, BCR-ABL1 positive: Regulation of these gene sets by HIF2α appears specific to AML cells as this was not observed in renal cancer, hematopoiesis, or a chronic myeloid leukemia (CML) cell line (Wierenga et al, 2014, 2019; Courtney et al, 2020).