cGAS‐STING pathway is a natural immune signaling pathway, the activation of which can secrete the type I interferons (IFNs) to promote dendritic cell (DC) maturation, and subsequently increased immune cell infiltration into the tumor microenvironment (TME) (e.g., natural killer cells [NKs] and cytotoxic T cells [CTLs]), thus eliciting an anti‐tumor immune response in vivo.[6] Therefore, immunotherapy based on activation of the cGAS‐STING pathway may prove effective in the treatment of UM. The gene discussed is CGAS; the disease is neoplasm.