Among these putative COVID‐19‐risk genes, we uncovered that 18 druggable genes with 154 interacting drugs obtained notably higher scDGSs (>120, FDR < 0.05) in brain endothelial cells, including top‐ranked genes of PLRKHA4, LTF, ICMA1, and P4HA2 (Figures 7K, S35, S36, and Table S21). The gene discussed is P4HA2; the disease is COVID-19.