Compared to HC, the total GSK3β level was statistically significantly lower in patients with BD (HC: 1.39 ± 0.10 SEM; UD: 0.91 ± 0.09 SEM; 95% Confidence Interval CI 0.12/0.84; p: 0.01) (Fig. 1A, C). The gene discussed is GSK3B; the disease is Behcet disease.