Bmal1 showed a main effect for epilepsy, F(1, 79) = 5.343; P < 0.05, time, F(4, 79) = 30.864; P < 0.01, and an epilepsy by time interaction, F(4, 79) = 7.206; P < 0.01 (Figure 1I–L). The gene discussed is BMAL1; the disease is epilepsy.