Regarding the risks conferred by FH, the SAFEHEART registry reported a more than 3 times prevalence of having angina pectoris, a 3.1-fold higher risk of acute myocardial infarction, and a tenfold chance of requiring coronary artery bypass surgery in the FH + group, compared with their unaffected relatives17. This evidence concerns the gene FH and myocardial infarction.