IHH and meningioma: To gain mechanistic insight into the relationship between the structural variations and ectopic expression of IHH, we perform genome-wide chromosome conformation capture (Hi-C) followed by H3K27ac ChIP-seq (HiChIP) analysis for chromatin interactions of meningiomas, comparing those with and without recurrent IHH tandem duplications, as well as H3K27ac ChIP-seq analysis for super-enhancer identification.