To investigate the reactivity of SIWA318M (the murine equivalent of SIWA318H) towards pancreatic cancer cells and stromal fibroblasts, we performed immunofluorescence staining of the antibody in PSN1 (pancreatic cancer cells) and CAF08 (pancreatic cancer-associated fibroblasts) cells with or without the treatment of etoposide, a topoisomerase inhibitor known to induce cellular senescence12. This evidence concerns the gene NT5C3A and familial pancreatic carcinoma.