FCGR3A and chronic myelogenous leukemia, BCR-ABL1 positive: As shown in the Fig. 3A, SIWA318H binds to human FcγRIIIa at an affinity similar to that of the positive control antibody (anti-CML monoclonal antibody, R&D Systems) (EC50: 59 vs. 13 μg/mL).