To investigate the cause of found discrepancies in PD-L1 expression between biopsy and resection specimens, we analyzed the staining patterns of PD-L1 expression in the resection specimens, the intensity of inflammation in the tumor stroma, and the correlation between the PD-L1 status of a tumor with clinical stage, grade, and lymph node involvement [Fig. 3]. This evidence concerns the gene CD274 and neoplasm.