Consistent with findings by Szczerba et al. [34], who reported a low incidence of somatic PVs in BRCA1/2 mutations in Polish patients with breast cancer, our research also revealed a relatively low incidence of somatic PV within the BRCA1/2 genes, ranging from 1% to 2.5%, in CRC patients. Here, BRCA1 is linked to colorectal carcinoma.