Apart from conventional cardiovascular risk factors such as blood pressure traits, cholesterol levels, type 2 diabetes, obesity and smoking, robust positive associations were observed between genetically predicted calcium (IVW OR: 1.66, 95%CI: 1.12-1.81) lymphocyte count (IVW OR:1.09, 95%CI:1.02 - 1.16), colony stimulating factor 1 (IVW OR: 1.19, 95%CI: 1.08 - 1.30) and omega 6 fatty acid levels (IVW OR: 1.21, 95%CI: 1.12-1.31) with CAD. Here, CSF1 is linked to coronary artery disorder.