YBX3 and Lyme disease: The difference in reactivityof B. burgdorferi s.l. antigens dependingon the genospecies from which they wereobtained is very common, even in proteins frequently used in commercialassays, such as DbpA and OspC, which are characterized by very highimmunogenicity and diversity.20,46 Therefore, in Europeit is advisable to use several variants of recombinant antigens indiagnostic tests to accurately detect cases of Lyme disease causedby different genospecies.