Although the titers of anti-DNA (anti-dsDNA) antibodies and the positivity of the other types of autoantibodies were not different in both groups, higher anti-β2GPI/HLA-DR antibody levels may reflect an over-expressed type I IFN signature and B-cell responses based on disease activity in patients with histories of arterial thrombosis. Here, APOH is linked to Arterial thrombosis.