IHC staining of the tumor xenograft tissue further demonstrated that silencing of PRMT1 to interfere with the interaction between PRMT1 and PGC-1α resulted in downregulated PGC-1α expression and the consequent growth inhibition of anoikis-resistant LMP1-positive NPC in vivo (Fig. 7K). This evidence concerns the gene PRMT1 and neoplasm.