The data illustrated that both the mRNA and protein levels of PD-L1 are inducible by PGC-1α, which suggests that PGC-1α might act as an inducer of PD-L1 in NPC cells and mediates the up-regulation of PD-L1 by LMP1 (Fig. 6C-D). Here, CD274 is linked to nasopharyngeal carcinoma.