In our study, compared with patients in the high ICW group who were less likely to have sarcopenic obesity (3.0% vs 41.3%), patients in the low ICW group had higher CRP levels; lower serum albumin; lower blood pressure; longer dialysis vintage; relatively advanced ages; and more complications, including DM, CVD and stroke, indicating that lower ICW and sarcopenic obesity might share a common pathogenesis. The gene discussed is ALB; the disease is stroke disorder.