To further investigate the correlation between CERCAM and different types of immune cell subpopulations, we analyzed the relationship between CERCAM expression in HNSCC and immune markers of different types of immune infiltrating cells (as shown in Table 4).The expression levels of CERCAM significantly correlated with marker genes of B cells, NK cells, monocytes, centrophages, DC cells, macrophages, M2 type macrophages, and T cells (including CD8 + T cells, Th1, Th2, Th9, Th17, Th22, and Tregs). Here, CERCAM is linked to head and neck squamous cell carcinoma.