The following 8 pathways of the top 20 pathways were activated when comparing to the HH vs. CON groups and the HH + CIA vs. CIA groups: ABC transporter pathways, purine metabolism, carbohydrate digestion and absorption, glutathione metabolism, steroid biosynthesis, basal cell carcinoma pathways, central carbon metabolism pathways in cancer, and primary bile acid biosynthesis. This evidence concerns the gene ABCG2 and cancer.