Sequencing of another set of gBRCA1/2mut breast tumors also showed high incidence of locus-specific LOH for BRCA1 (90%); however, lower LOH incidence (54%) was observed for BRCA2. In that dataset, LOH for BRCA1 was more commonly copy neutral and loss of the wildtype allele more frequent in gBRCA2mut tumors16. Here, BRCA1 is linked to breast neoplasm.