BRCA2 and neoplasm: Across both cohorts, the most common tumor BRCA1/2 variant types detected were single nucleotide variants (BRCA1: 15/60, 25.0%; BRCA2: 11/60, 18.3%), deletions (BRCA1: 11/60, 18.3%; BRCA2: 12/60, 20.0%), and insertions (BRCA1: 4/60, 6.7%; BRCA2: 6/60, 10.0%), with a tumor BRCA1 copy number alteration (CNA) only evident in 1/60 patients (Supplementary Table 1 [patient 16]).