BRCA1 and neoplasm: Of the remaining three of 40 patients, one (patient 60) exhibited BRCA LOH with tumor retention of a presumed somatic (i.e., not detected in germline testing) BRCA1 mutation, with a different known gBRCAmut predicted to be in a heterozygous state in the tumor; gBRCAmut details were not available for the other two patients (patients 21 and 37) (Supplementary Table 1).