G6PD and small cell lung carcinoma: The CCK8 assay showed that compared with cells in the mock-vehicle groups, cells transfected with the G6PD overexpression vector had higher cell proliferation rates when exposed to GSK2126458 alone, IR alone, or the combination of GSK2126458 and IR, suggesting that G6PD played a crucial role in SCLC radioresistance (Fig. 6G).