KMT2A and acute myeloid leukemia: Indeed, exposure of the murine pro-B cell line BA/F3 or the leukaemic cell lines THP1 (MLL-AF9+; AML) or K562 (BCR-ABL1+; chronic myeloid leukaemia (CML)), stably transfected with this construct, to increasing calcium concentrations enhanced GFP fluorescence (Supplementary Fig. 1b–g, Supplementary Table 1).