CASR and leukemia: Hypothesising that differences in the extracellular calcium concentration may influence pathophysiological features of normal haematopoietic and leukaemia cells, possibly via CaSR, we, firstly, confirmed3 that CaSR levels were higher on normal murine haematopoietic stem cells compared to more differentiated haematopoietic cells (Supplementary Fig. 3a–c).