As shown in Figure 6A, eight were selected, five upregulated and five regulated genes, and one of the DEGs, DEPP, was significantly positively correlated with PLCL1, exhibiting the highest correlation coefficient (R2 = 0.51, P < 0.001) in mRNA expression based on Pearson’s correlation of TCGA RCC tumours (Figure 6B). The gene discussed is DEPP1; the disease is renal cell carcinoma.