Elevated preoperative levels of fibrinogen, cystatin-C, C-reactive protein (CRP), and neutrophil-to-lymphocyte ratio (NLR) (> 2.7) are associated with LN involvement, as well as low albumin-globulin ratio (AGR) (< 1.45), and preoperative anemia [31–36]. The gene discussed is CRP; the disease is anemia (phenotype).