Prolonged QRS duration in MI vs. Sham and Treatment could be the result of reductions in the rapid delayed rectifier K + channel Kv11.1/Kcnh2 and reduced cellular coupling via gap junctions, as indicated by lower expression of Gja1 (Connexin 43) (Fig. 8F), a result confirmed by semi-quantitative real-time PCR (Fig S2). Here, GJA1 is linked to myocardial infarction.