The previous studies also proved the role of cell cycle pathway in GC, where the cell cycle pathway is regulated by lncRNA CASC11, which promotes the migration and invasion of GC cells.[24] Furthermore, it has been proven that the cell cycle pathway plays a key role in GC cell migration, and that NT5DC2 knockdown can also reduce NSCLC migration.[13] Taken together, we suggested that NT5DC2 might induce the metastases process of GC by promoting the cell cycle pathway. The gene discussed is NT5DC2; the disease is gastric cancer.