HDAC3 and autism spectrum disorder: Ankrd11, a potential chromatin regulator, is associated with neurodevelopment and autism spectrum disorder.[7,8] Knockdown of Ankrd11 expression in mice can slow down the proliferation and production of embryonic cortical neuron precursors, and lead to abnormal localization of neurons.[9,10] Studies have shown that Ankrd11 is in connection with chromatin acetylation and involves in colocalization with HDAC3.