EGFR and head and neck squamous cell carcinoma: The development of effective therapeutic agents for HNSCC may benefit from research into the role of phytochemicals that target epidermal growth factor receptors in HNSCC.[14,15] Throughout the investigation, we discovered that the majority of studies relied on cellular and animal models.[16] The effectiveness of herbal chemical agents in HNSCC via EGFR should therefore be the subject of additional extensive clinical studies.