Spinal posture and mobility were not different in adults with Prader-Willi syndrome who were treated with recombinant growth hormone (rec-GH) during (6 females, 7 males) or before the study period (10 females, 11 males) compared to those with Prader-Willi syndrome never treated with rec-GH (p>0.05). The gene discussed is GH1; the disease is Prader-Willi syndrome.