PIK3R1 and neoplasm: The experimental results showed that compared with the control group, the expression of Pik3r1, Akt1, Myc, Egfr, Hif1a, Vegfr, Jun, and Stat3 genes in the tumor tissue of mice in the BZD group was significantly reduced, and the Casp3 and Trp53 genes expression was significantly increased; this is consistent with the predicted results of network pharmacology.