Interestingly, the expression levels of CLDN5 and CLDN11 are positively associated with the activity of cell adhesion molecules CAMs, ECM receptor interaction, ERBB signaling pathway, focal adhesion, gap junction, leukocyte transendothelial migration, MAPK signaling pathway, MTOR signaling, Notch signaling, pathways in cancer, TGF beta signaling, tight junction, VEGF signaling pathway, and Wnt signaling (Figure 10). Here, CLDN5 is linked to cancer.