CLDN8 and neoplasm: Using public datasets GSE15781 and GSE50760 from NCBI-GEO (https://www.ncbi.nlm.nih.gov/geo/), we validated CLDN1, CLDN2, and CLDN14 to be significantly upregulated and CLDN8 and CLDN23 to be significantly downregulated in normal colon versus tumor tissues from human samples.