As a widely acknowledged tool to evaluate the quality of diagnostic meta-analysis [15], we used QUADAS-2 tool to control the quality of this research.,ABPA is a mysterious issue, which is an inflammatory diseased induced by infection, and it is a type I and type III hypersensitivity-mediated allergic reaction to Aspergillus, and various inflammatory mediators were induced by Aspergillus conidia, including interleukin (IL)-4, IL-5, IL-13 and other cytokines, and inflammatory cells such as eosinophils would be also stimulated [26]. Here, IL4 is linked to infection.