Gelatinase MMPs such as matrix metalloproteinase − 9 (MMP-9) and matrix metalloproteinase − 2 (MMP-2) overexpression are associated with oral cancer, colorectal tumor, bladder carcinoma, retinoblastoma, pancreatic cancer, and ovarian cancer [5–10]. The gene discussed is MMP9; the disease is lip and oral cavity carcinoma.