It is worth commenting that patients’ survival was not substantially altered by isolated or combined genotypes of GSTP1 c.313A>G, EXO1 c.1765G>A, and MSH3 c.3133G>A SNVs in the current analysis of this study, but GSTP1 c.313GG genotype was associated with lower EFS in a previous analysis of the same cohort of patients (n = 90)14 and EXO1 c.1765GG and MSH3 c.3133GG genotypes were associated with lower EFS and OS, respectively, in a large sample of HNSCC (n = 397) analyzed previously by our group16. Here, GSTP1 is linked to head and neck squamous cell carcinoma.