ACAA2 and central nervous system cancer: We also assessed ACAA2 mRNA levels in CCLE [34] to demonstrate that ACAA2 mRNA expression is also significantly increased in SCLC (N = 50) and neuroblastoma cell lines (N = 16), both of which are NE cancers, relative to their non-NE counterparts: NSCLC (N = 120) and glioma (N = 53) (Fig. 4b and Supplementary Fig. S4A, B).