NPPB and atrial fibrillation: In a further step, we compared the combined biomarker model (age, sex, BMI, BMP10, ANGPT2, FGF23) with NTproBNP in patients ≥ 75 years old (n = 509; AF = 302, SR = 207) mirroring STROKESTOPII criteria and demonstrated that the biomarkers were better able to identify patients with AF compared to NTproBNP (Supplemental Material Fig. S6).