As per the literature review, the expression of E2F1 is up-regulated in TP53-knockdown cells.29 In our study, E2F1 expression levels were significantly higher in TP53mut DLBCL patients (Supplementary Fig. 4d) and TP53mut cell lines (Supplementary Fig. 4e and 4f) than TP53wt counterparts. The gene discussed is TP53; the disease is diffuse large B-cell lymphoma.