We observed increased expression of a specific set of genes in MLL rearrangement patients including GRK2, KCNE5, AZU1, TRPM4, and C4orf48. G protein-coupled receptor kinase 2 (GRK2) has been shown to associate with HSP90 in AML cells31. The gene discussed is GRK2; the disease is acute myeloid leukemia.