CTSS and neoplasm: One patient with AMKL (patient 17) who died, exhibited overexpression of genes like S100A11, LST1, CEBP, SERPINA1, CTSS, FCER1G, and IFITM2. IFITM2 expression is associated with TGFβ mediated epithelial–mesenchymal transition in gastric cancer40 while SERPINA1 which encodes acute phase protein, alpha 1 antitrypsin (AAT) is associated with tumor cell migration, colony formation, and resistance to apoptosis41.