BCL2 and Infertility: Similarly, Mokhtari Amirmajdi et al., showed that the Caspase-3 activity and the ratio of Bax/Bcl-2 mRNA expression were higher in PSCs-treated lymphocytes relative to infertile fluid-treated lymphocytes and control group which exhibited apoptosis could be as a possible mechanism by which E. granulosus overwhelms host defenses [23].