AFP and hepatocellular carcinoma: The differences in epidemiological and physiological characteristics, including age, sex, ethnicity, Eastern Cooperative Oncology Group performance status, etiology of disease, Child-Pugh class, Barcelona Clinic Liver Cancer (BCLC) stage, extrahepatic spread of disease, macrovascular invasion, alpha-fetoprotein concentration, and previous treatment history in patients diagnosed as advanced HCC, could result in needs for modelling which is more associated with these differences.