Stratified by the new WHO classification, there were no significant results in IDH-mutant astrocytoma grade 2 (p = 0.891, Fig 3B), grade 3 (p = 0.502, Fig 3C), and grade 4 (p = 0.160, Fig 3D). The gene discussed is IDH1; the disease is astrocytoma (excluding glioblastoma).