Giordo et al. (Giordo et al. 2021) proposed that in virtue of its anti-thrombotic, antioxidant, and anti-inflammatory effects, resveratrol can reduce OS, inflammatory disorders, and thrombotic events in COVID-19 through activation of the Nrf2/HO-1 pathway (Giordo et al. 2021). This evidence concerns the gene NFE2L2 and COVID-19.