Proteomic data verified that LDHA, HK2, NCOR2, CAV1, CCND1, OAS2, VEGFA, MED1, and PAM were significantly higher expressed, while PFKFB2, LDHB, PNKD, LDHD, HAGH, SLC16A7, SLC5A12, GOT2, and SLC25A12 were lower expressed in tumor samples (Figure S1D; Supplementary Table 1). The gene discussed is PFKFB2; the disease is neoplasm.