The chromosome 9p21.3 region is deleted in approximately 15% of cancers (3, 4) and contains the tumour suppressor gene cyclin-dependent kinase inhibitor 2A (CDKN2A). This gene encodes for the p14 (5) and p16 (6) proteins that stabilise p53 and block G1 progression respectively. This evidence concerns the gene CDKN2A and cancer.