SPH1 (Spherocytosis, type 1), SPH2 (Spherocytosis, type 2), SPH3 (Spherocytosis, type 3), SPH4 (Spherocytosis, type 4), SPH5 (Spherocytosis, type 5) are caused by ANK1, SPTB, SPTA1, SLC4A1, and EPB42 gene mutations, respectively (He et al., 2018). The gene discussed is SPTA1; the disease is Spherocytosis.