The strongest association with severe COVID-19 was observed for genomic locus 3p21.31 covering genes SLC6A20, LZTFL1, CCR9, FYCO1, CXCR6 and XCR1. Another signal was detected from 9q34.2, that overlaps with the ABO blood group locus. The gene discussed is XCR1; the disease is COVID-19.