The differentially enriched gene sets in the high ARPC1B expression phenotype were found to be associated with several immunoregulatory genes, which included those involved in antigen processing and presentation, asthma, autoimmune thyroid disease, cytosolic DNA sensor pathway, graft versus host disease, intestinal immune network for IgA production, Leishmania infection, system lupus erythematosus, and type I diabetic mellitus (Figure 8C). Here, ARPC1B is linked to type 1 diabetes mellitus.