The enrichment of GO annotation and pathway analysis showed that ARPC1B affected tumorigenesis and progression through multiple immune-related functions and pathways, such as regulation of immune effector process, regulation of inflammatory response, antigen processing and presentation, asthma, autoimmune thyroid disease, graft versus host disease, intestinal immune network for IgA production, and type I diabetic mellitus. The gene discussed is ARPC1B; the disease is autoimmune thyroid disease.